The Essential Toxin: Impact of Zinc on Human Health

  title={The Essential Toxin: Impact of Zinc on Human Health},
  author={Laura Marie Plum and Lothar Rink and Hajo Haase},
  booktitle={International journal of environmental research and public health},
Compared to several other metal ions with similar chemical properties, zinc is relatively harmless. Only exposure to high doses has toxic effects, making acute zinc intoxication a rare event. In addition to acute intoxication, long-term, high-dose zinc supplementation interferes with the uptake of copper. Hence, many of its toxic effects are in fact due to copper deficiency. While systemic homeostasis and efficient regulatory mechanisms on the cellular level generally prevent the uptake of… CONTINUE READING
151 Citations
179 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 151 extracted citations


Publications referenced by this paper.
Showing 1-10 of 179 references

Clinical manifestations of zinc deficiency

  • A. S. Prasad
  • Annu. Rev. Nutr. 1985,
  • 1985
Highly Influential
4 Excerpts

Similar Papers

Loading similar papers…