The Esophageal Multimodal Pain Model: Normal Values and Degree of Sensitization in Healthy Young Male Volunteers

@article{Krarup2010TheEM,
  title={The Esophageal Multimodal Pain Model: Normal Values and Degree of Sensitization in Healthy Young Male Volunteers},
  author={Anne Lund Krarup and Magnus Simr{\'e}n and Peter M Funch-Jensen and Mark Berner Hansen and Frederik Hvid-Jensen and Jan Brun and Asbj\orn Mohr Drewes},
  journal={Digestive Diseases and Sciences},
  year={2010},
  volume={56},
  pages={1967-1975}
}
Sensory changes are thought to be involved in gastro-esophageal reflux disease (GERD). The esophageal multimodal pain model can be used to investigate sensations in response to distension, heat, electric current and acid. The aim of this study was to provide normal values for this model in the normal state and in the acid induced sensitized state. Fifty-three healthy men (20–38 years old) underwent esophageal stimulation with distension, heat and electrical current before and after… CONTINUE READING