The Escherichia coli Lpt transenvelope protein complex for lipopolysaccharide export is assembled via conserved structurally homologous domains.

@article{Villa2013TheEC,
  title={The Escherichia coli Lpt transenvelope protein complex for lipopolysaccharide export is assembled via conserved structurally homologous domains.},
  author={R. Villa and A. Martorana and Suguru Okuda and L. Gourlay and M. Nardini and P. Sperandeo and G. Deh{\`o} and M. Bolognesi and D. Kahne and A. Polissi},
  journal={Journal of bacteriology},
  year={2013},
  volume={195 5},
  pages={
          1100-8
        }
}
Lipopolysaccharide is a major glycolipid component in the outer leaflet of the outer membrane (OM), a peculiar permeability barrier of Gram-negative bacteria that prevents many toxic compounds from entering the cell. Lipopolysaccharide transport (Lpt) across the periplasmic space and its assembly at the Escherichia coli cell surface are carried out by a transenvelope complex of seven essential Lpt proteins spanning the inner membrane (LptBCFG), the periplasm (LptA), and the OM (LptDE), which… Expand
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69 Citations

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Functional Interaction between the Cytoplasmic ABC Protein LptB and the Inner Membrane LptC Protein, Components of the Lipopolysaccharide Transport Machinery in Escherichia coli.
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The Lack of the Essential LptC Protein in the Trans-Envelope Lipopolysaccharide Transport Machine Is Circumvented by Suppressor Mutations in LptF, an Inner Membrane Component of the Escherichia coli Transporter
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Structural and functional insights into the lipopolysaccharide ABC transporter LptB2FG
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Disruption of the E. coli LptC dimerization interface and characterization of lipopolysaccharide and LptA binding to monomeric LptC
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Trapped lipopolysaccharide and LptD intermediates reveal lipopolysaccharide translocation steps across the Escherichia coli outer membrane
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Characterization of lipopolysaccharide transport protein complex
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Thanatin Impairs Lipopolysaccharide Transport Complex Assembly by Targeting LptC–LptA Interaction and Decreasing LptA Stability
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Structural insight into lipopolysaccharide transport from the Gram-negative bacterial inner membrane to the outer membrane.
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Crystal structure of LptH, the periplasmic component of the lipopolysaccharide transport machinery from Pseudomonas aeruginosa
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Structural basis for outer membrane lipopolysaccharide insertion
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References

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