The Escherichia coli K-12 SOS chromotest agar spot test for simple, rapid detection of genotoxic agents.

Abstract

The Escherichia coli K-12 SOS chromotest is a colorimetric (beta-galactosidase induction) system for detecting genotoxic chemicals as agents which induce filamentation in response to DNA damage. The chromotest was modified from a liquid suspension assay to a simple, convenient agar spot test, which was performed in the manner of a related colorimetric… (More)

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