The Erv family of sulfhydryl oxidases.

  title={The Erv family of sulfhydryl oxidases.},
  author={Deborah Fass},
  journal={Biochimica et biophysica acta},
  volume={1783 4},
The Erv flavoenzymes contain a compact module that catalyzes the pairing of cysteine thiols into disulfide bonds. High-resolution structures of plant, animal, and fungal Erv enzymes that function in different contexts and intracellular compartments have been determined. Structural features can be correlated with biochemical properties, revealing how core sulfhydryl oxidase activity has been tailored to various functional niches. The introduction of disulfides into cysteine-containing substrates… CONTINUE READING