The Epstein-Barr virus-encoded nuclear antigen EBNA-5 accumulates in PML-containing bodies.

@article{Szkely1996TheEV,
  title={The Epstein-Barr virus-encoded nuclear antigen EBNA-5 accumulates in PML-containing bodies.},
  author={L{\'a}szl{\'o} Sz{\'e}kely and Katja Pokrovskaja and Weining Jiang and Hugues de Th{\'e} and Nils R. Ringertz and George Klein},
  journal={Journal of virology},
  year={1996},
  volume={70 4},
  pages={2562-8}
}
EBNA-5 is one of the Epstein-Barr virus (EBV)-encoded nuclear proteins required for immortalization of human B lymphocytes. In the nuclei of EBV-transformed lymphoblastoid cell lines EBNA-5 is preferentially targetted to distinct nuclear foci. Previously we have shown (W.Q. Jiang, L. Szekely, V. Wendel-Hansen, N. Ringertz, G. Klein, and A. Rosen, Exp. Cell Res. 197:314-318, 1991) that the same foci also contained the retinoblastoma (Rb) protein. Using a similar double immunofluorescence… CONTINUE READING