The Epstein–Barr virus and the pathogenesis of lymphoma

  title={The Epstein–Barr virus and the pathogenesis of lymphoma},
  author={M. Vockerodt and L. Yap and C. Shannon-Lowe and H. Curley and W. Wei and K. Vrzalikova and P. Murray},
  journal={The Journal of Pathology},
  • M. Vockerodt, L. Yap, +4 authors P. Murray
  • Published 2015
  • Medicine
  • The Journal of Pathology
  • Since the discovery in 1964 of the Epstein–Barr virus (EBV) in African Burkitt lymphoma, this virus has been associated with a remarkably diverse range of cancer types. Because EBV persists in the B cells of the asymptomatic host, it can easily be envisaged how it contributes to the development of B‐cell lymphomas. However, EBV is also found in other cancers, including T‐cell/natural killer cell lymphomas and several epithelial malignancies. Explaining the aetiological role of EBV is… CONTINUE READING
    121 Citations

    Topics from this paper

    The Role of Epstein–Barr Virus in Cervical Cancer: A Brief Update
    • 15
    • PDF
    Epstein-Barr Virus and Classical Hodgkin’s Lymphoma
    • 1
    • PDF
    Current Trends and Alternative Scenarios in EBV Research.
    • 5
    • PDF
    The role of Epstein–Barr virus in epithelial malignancies
    • 181
    The Function and Therapeutic Potential of Epstein-Barr Virus-Encoded MicroRNAs in Cancer
    • 7
    Epstein–Barr Virus: Diseases Linked to Infection and Transformation
    • 49
    • Highly Influenced
    • PDF


    Burkitt lymphoma: the role of Epstein‐Barr virus revisited
    • 31
    Epstein-Barr Virus and the Pathogenesis of T and NK Lymphoma: a Mystery Unsolved
    • 23
    Co-infections, inflammation and oncogenesis: future directions for EBV research.
    • 116
    Epstein-Barr virus, the germinal centre and the development of Hodgkin's lymphoma.
    • 9
    Epstein-Barr virus provides a survival factor to Burkitt's lymphomas
    • 255
    • PDF
    Demonstration of the Burkitt's lymphoma Epstein-Barr virus phenotype in dividing latently infected memory cells in vivo
    • 276
    • PDF
    Epstein-Barr virus and its role in the pathogenesis of Burkitt's lymphoma: an unresolved issue.
    • G. Bornkamm
    • Biology, Medicine
    • Seminars in cancer biology
    • 2009
    • 58
    A Molecular Link between Malaria and Epstein–Barr Virus Reactivation
    • 149
    • PDF
    The company malaria keeps: how co-infection with Epstein–Barr virus leads to endemic Burkitt lymphoma
    • 71