The Epigenetic Landscape in the Treatment of Gynecologic Malignancies.

  title={The Epigenetic Landscape in the Treatment of Gynecologic Malignancies.},
  author={Ramez N. Eskander},
  journal={American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting},
  • R. Eskander
  • Published 23 May 2018
  • Medicine, Biology
  • American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting
The care of patients with advanced-stage or recurrent endometrial, ovarian, and cervical cancer remains clinically challenging. Despite the identification of novel therapeutics and advancements in supportive care, survival outcomes have been relatively unchanged over the past decade. In addition to established genomic alterations and the contributions of the tumor microenvironment to cancer progression, epigenetic mechanisms have emerged as important contributors to gynecologic cancer… 

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