The Epidemiology and Etiology of Keratoconus

@inproceedings{GordonShaag2012TheEA,
  title={The Epidemiology and Etiology of Keratoconus},
  author={Ariela Gordon-Shaag and Michel Millodot and Einat Shneor},
  year={2012}
}
Keratoconus is a noninflammatory disorder characterized by ectasia of the central or inferior portion of the cornea. This review presents the scant epidemiological information known to date and the factors believed to cause the development of the disease. They are the genetic factors for which evidence come from family studies, twin studies and genetic loci. There appears to be multiple genes causing a keratoconus phenotype with variable penetration. However, the genetic predisposition might… 
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TLDR
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TLDR
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Is Consanguinity a Risk Factor for Keratoconus?
TLDR
Wearing sunglasses in this environment is beneficial, and the study confirmed that eye rubbing, allergy, and education are also significantly associated with KC after adjusting for other predictors.
The correlation between keratoconus and eye rubbing: a review.
TLDR
It is concluded that eye rubbing causes the thinning of keratocyte, and the degree of effect of eye rubbing depends on the period and force of performing eye rubbing.
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