The Elp2 subunit is essential for elongator complex assembly and functional regulation.

@article{Dong2015TheES,
  title={The Elp2 subunit is essential for elongator complex assembly and functional regulation.},
  author={Chunming Dong and Zhijie Lin and Wentao Diao and Dan Li and Xinlei Chu and Zheng Wang and Hao David Zhou and Zhiping Xie and Yuequan Shen and Jiafu Long},
  journal={Structure},
  year={2015},
  volume={23 6},
  pages={1078-86}
}
Elongator is a highly conserved multiprotein complex composed of six subunits (Elp1-6). Elongator has been associated with various cellular activities and has attracted clinical attention because of its role in certain neurodegenerative diseases. Here, we present the crystal structure of the Elp2 subunit revealing two seven-bladed WD40 β propellers, and… CONTINUE READING