The Efficacy of Probiotic (Lactobacillus rhamnosus GG) and 5-ASA (Aminosalicylic Acid) in the Treatment of Experimental Radiation Proctitis in Rats.

@article{Dandin2015TheEO,
  title={The Efficacy of Probiotic (Lactobacillus rhamnosus GG) and 5-ASA (Aminosalicylic Acid) in the Treatment of Experimental Radiation Proctitis in Rats.},
  author={{\"O}zg{\"u}r Dandin and Mehmet Levhi Akin and A Z Balta and Erg{\"u}n Y{\"u}cel and Dursun {\"O}zg{\"u}r Karakaş and Sezai Demirbaş and Sevim {\"O}zdemir and Apdullah Haholu},
  journal={The Indian journal of surgery},
  year={2015},
  volume={77 Suppl 2},
  pages={563-9}
}
The aims of the study are to demonstrate the effect of probiotic use on the healing of radiation proctitis (RP) and evaluate the efficiency of fecal biomarkers at follow-up of the treatment. Thirty-two male/female rats were randomly separated into four groups of eight rats. The first group (control) was not radiated. RP was created by 17.5 Gy single dose rectal irradiation. The second group (RP) was subjected to RP, but not treated. The third group (RP+ASA) was treated with 5-aminosalicylic… CONTINUE READING