The Efficacy and Safety of Tolvaptan in Patients with Hyponatremia: A Meta-Analysis of Randomized Controlled Trials.

BACKGROUND AND OBJECTIVES Comprehensive evaluations regarding the benefits of tolvaptan in the treatment of hyponatremia are lacking. The objective of this meta-analysis was to assess the efficacy and safety of tolvaptan in patients with hyponatremia. METHODS Pertinent studies were identified by searching PubMed, EMBASE, Web of Science, and the Cochrane… CONTINUE READING