The Efficacy and Safety of Tanacetum Parthenium (Feverfew) in Migraine Prophylaxis—a Double-Blind, Multicentre, Randomized Placebo-Controlled Dose-Response Study

@article{Pfaffenrath2002TheEA,
  title={The Efficacy and Safety of Tanacetum Parthenium (Feverfew) in Migraine Prophylaxis—a Double-Blind, Multicentre, Randomized Placebo-Controlled Dose-Response Study},
  author={V. Pfaffenrath and H. Diener and M. Fischer and M. Friede and H. Henneicke-von Zepelin},
  journal={Cephalalgia},
  year={2002},
  volume={22},
  pages={523 - 532}
}
  • V. Pfaffenrath, H. Diener, +2 authors H. Henneicke-von Zepelin
  • Published 2002
  • Medicine
  • Cephalalgia
  • Tanacetum parthenium (feverfew), is a well-known herb for the prophylactic treatment of migraine. The primary objective was to show a dose-response of a new stable extract (MIG-99) reproducibly manufactured with supercritical CO2 from feverfew (T. parthenium). Furthermore, the study should provide data on the safety and tolerability of MIG-99. In a randomized, double-blind, multicentre, controlled trial with an adaptive design, the clinical efficacy and safety of three dosages of MIG-99 (2.08… CONTINUE READING
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