The Efficacy and Safety of Drug Treatments for Chronic Insomnia in Adults: A Meta-analysis of RCTs

  title={The Efficacy and Safety of Drug Treatments for Chronic Insomnia in Adults: A Meta-analysis of RCTs},
  author={Nina Buscemi and B. Vandermeer and Carol Friesen and Liza Bialy and Michelle Tubman and Maria B. Ospina and Terry P Klassen and Manisha Witmans},
  journal={Journal of General Internal Medicine},
BackgroundHypnotics have a role in the management of acute insomnia; however, the efficacy and safety of pharmacological interventions in the management of chronic insomnia is unclear. [] Key MethodData SourcesTwenty-one electronic databases were searched, up to July 2006.Study SelectionRandomized double-blind, placebo-controlled trials were eligible. Quality was assessed using the Jadad scale. Data were pooled using the random effects model.

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