The Effects of a Subpsychotic Dose of Ketamine on Recognition and Source Memory for Agency: Implications for Pharmacological Modelling of Core Symptoms of Schizophrenia

@article{Honey2006TheEO,
  title={The Effects of a Subpsychotic Dose of Ketamine on Recognition and Source Memory for Agency: Implications for Pharmacological Modelling of Core Symptoms of Schizophrenia},
  author={Garry D. Honey and C O'loughlin and Danielle C. Turner and Edith Pomarol-Clotet and Philip Corlett and Paul C. Fletcher},
  journal={Neuropsychopharmacology},
  year={2006},
  volume={31},
  pages={413-423}
}
Ketamine is increasingly used to model the cognitive deficits and symptoms of schizophrenia. We investigated the extent to which ketamine administration in healthy volunteers reproduces the deficits in episodic recognition memory and agency source monitoring reported in schizophrenia. Intravenous infusions of placebo or 100 ng/ml ketamine were administered to 12 healthy volunteers in a double-blind, placebo-controlled, randomized, within-subjects study. In response to presented words, the… CONTINUE READING
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Multinomial processing models of source monitoring

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Highly Influential
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