The Effects of TLR Activation on T-Cell Development and Differentiation

  title={The Effects of TLR Activation on T-Cell Development and Differentiation},
  author={Bo Jin and Tao Sun and Xiao-hong Yu and Ying-xiang Yang and Anthony E. T. Yeo},
  booktitle={Clinical & developmental immunology},
Invading pathogens have unique molecular signatures that are recognized by Toll-like receptors (TLRs) resulting in either activation of antigen-presenting cells (APCs) and/or costimulation of T cells inducing both innate and adaptive immunity. TLRs are also involved in T-cell development and can reprogram Treg cells to become helper cells. T cells consist of various subsets, that is, Th1, Th2, Th17, T follicular helper (Tfh), cytotoxic T lymphocytes (CTLs), regulatory T cells (Treg) and these… CONTINUE READING


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Oral tolerance

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  • Immunological Reviews, vol. 241, no. 1, pp. 241…
  • 2011
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