The Effects of Prucalopride on Postoperative Ileus in Guinea Pigs

@inproceedings{Park2013TheEO,
  title={The Effects of Prucalopride on Postoperative Ileus in Guinea Pigs},
  author={Soo Jung Park and Eun Ju Choi and Young Hoon Yoon and Hyojin Park},
  booktitle={Yonsei medical journal},
  year={2013}
}
PURPOSE Postoperative ileus (POI) is an impairment of coordinated gastrointestinal (GI) motility that develops as a consequence of abdominal surgery and is a major factor contributing to patient morbidity and prolonged hospitalization. The aim of this study was to investigate the effects of different 5-hydroxytryptamine 4 (5-HT₄) receptor agonists, which stimulate excitatory pathways, on a POI model. MATERIALS AND METHODS The experimental model of POI in guinea pigs was created by laparotomy… CONTINUE READING

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