The Effects of Progesterone Therapy on the Gestation Length and Reduction of Neonatal Complications in Patients who had Received Tocolytic Therapy for Acute Phase of Preterm Labor

@article{Lotfalizadeh2013TheEO,
  title={The Effects of Progesterone Therapy on the Gestation Length and Reduction of Neonatal Complications in Patients who had Received Tocolytic Therapy for Acute Phase of Preterm Labor},
  author={Marzieh Lotfalizadeh and Nayereh Ghomian and Amirreza Reyhani},
  journal={Iranian Red Crescent Medical Journal},
  year={2013},
  volume={15}
}
Background While tocolytic therapy can halt the process of delivery, some patients return before the 37th week of pregnancy with recurrence of preterm labor signs. Objectives This study was designed to evaluate the efficacy of progesterone in the prolonging of gestation and reduction of neonatal complications. Material and Methods In a clinical trial in 2010, 110 singleton pregnant women admitted at Imam Reza Hospital, Mashhad, Iran, with the diagnosis of preterm labor were divided into three… 
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The Effect of Oral Progesterone on Deceasing Preterm Labor in Patients with a History of Preterm Labor
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Using 100 mg oral progesterone per day in weeks 16-36 of pregnancy was effective in reduction of preterm labor, and caused improved gestational age in mothers, based on the results of the current study.
Use of progesterone supplement therapy for prevention of preterm birth: review of literatures
  • Suk-Joo Choi
  • Medicine, Biology
    Obstetrics & gynecology science
  • 2017
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The efficacy and safety of progesterone supplement therapy on prevention of PTB is summarized according to different indication, type, route, and dose of progestersone, based on the results of recent randomized trials and meta-analysis.
Progesterone in women with arrested premature labor, a report of a randomised clinical trial and updated meta-analysis
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Vaginal progesterone treatment is not effective for preventing preterm birth following arrested preterm labor and an updated meta-analysis shows this effect was not evident in the high quality trials.
Progestogens as Maintenance Treatment in Arrested Preterm Labor: A Systematic Review and Meta-analysis
TLDR
There is insufficient high-quality data to inform clinicians and patients about the use of progestogens as maintenance treatment after arrested preterm labor to reduce the incidence of preterm birth or pregnancy prolongation.
Vaginal progesterone for preterm birth prevention in women with arrested preterm labor.
  • H. FreyM. Stout A. Cahill
  • Medicine
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
  • 2021
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This randomized controlled trial and meta-analysis do not support the use of vaginal progesterone for the prevention of preterm birth in women who present in preterm labor.
Vaginal progesterone for maintenance tocolysis: a systematic review and metaanalysis of randomized trials.
Effect of vaginal progesterone in tocolytic therapy during preterm labor in twin pregnancies: Secondary analysis of a placebo‐controlled randomized trial
Our aim was to investigate the effect of the prophylactic use of vaginal progesterone on the latency period from the initiation of tocolytic therapy to delivery in twin pregnancies with preterm labor.
Effects of vaginal progesterone for maintenance tocolysis on uterine electrical activity
TLDR
The effects of vaginal progesterone on uterine EMG after successful acute tocolysis is examined and myometrial contractility can be assessed objectively and non‐invasively after progester one treatment by monitoring uterine electromyography (EMG).
17OHP‐C in patients with spontaneous preterm labor and intact membranes: is there an effect according to the presence of intra‐amniotic inflammation?
It is not known whether 17‐alpha‐hydroxyprogesterone caproate (17OHP‐C) is effective for preventing preterm delivery with an episode of preterm labor (PTL) with or without intra‐amniotic…
17-alpha-hydroxyprogesterone Caproate for Maintenance Tocolysis: A Systematic Review and Metaanalysis of Randomized Trials
TLDR
Electronic databases used to evaluate the efficacy of maintenance tocolysis with 17-alpha-hydroxyprogesterone caproate compared to control in singleton gestations with arrested preterm labor were searched from 1966 through July 2014.
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