The Effects of Morphine on Tissue Structure of the Growth Plate in Male Rats

  title={The Effects of Morphine on Tissue Structure of the Growth Plate in Male Rats},
  author={Massood Ezzatabadipour and Masoud Majidi and Reza Malekpour-afshar and Seyed Hasan Eftekharvaghefi and Seyed Noureddin Nematollahi-Mahani},
  booktitle={Iranian journal of basic medical sciences},
OBJECTIVES Studies have shown that morphine, in addition to its analgesic properties, has several effects on cell proliferation and apoptosis. There is also evidence that opioid receptors are present on chondrocytes. Our main objective in the present study was to investigate the effects of morphine on rat femur growth cartilage. MATERIALS AND METHODS This research was carried out on 18 4-week-old male rats. Animals were divided into four groups: groups 1 (n= 3) and 2 (n= 4) were non morphine… CONTINUE READING


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