The Effects of Gap Junction Blockage on Neuronal Differentiation of Human NTera2/Clone D1 Cells

@article{BaniYaghoub1999TheEO,
  title={The Effects of Gap Junction Blockage on Neuronal Differentiation of Human NTera2/Clone D1 Cells},
  author={Mahmud Bani‐Yaghoub and John F. Bechberger and T. Michael Underhill and Christian C. G. Naus},
  journal={Experimental Neurology},
  year={1999},
  volume={156},
  pages={16-32}
}
Gap junctions are intercellular channels which provide for the passage of small ions and molecules (MW <1200 D) among adjacent cells. The NTera2/clone D1 (NT2/D1) cells are CNS precursors which differentiate into NT2-N neurons upon treatment with retinoic acid (RA) and antiproliferative agents. In this study, the effects of gap junction blockers 18 alpha-glycyrrhetinic acid (GRA) and carbenoxolone (CBX) have been compared with those of oleanolic acid (OLA) and glycyrrhizic acid (GZA), GRA… 

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