The Effects of Fibrinogen Levels on Thromboelastometric Variables in the Presence of Thrombocytopenia

  title={The Effects of Fibrinogen Levels on Thromboelastometric Variables in the Presence of Thrombocytopenia},
  author={Thomas Lang and K. Johanning and H. Metzler and S. Piepenbrock and C. Solomon and N. Rahe-meyer and K. Tanaka},
  journal={Anesthesia & Analgesia},
  • Thomas Lang, K. Johanning, +4 authors K. Tanaka
  • Published 2009
  • Medicine
  • Anesthesia & Analgesia
  • BACKGROUND: The binding of fibrinogen and fibrin to platelets is important in normal hemostasis. The extent of platelet-fibrin interaction can be measured as the viscoelastic strength of clot by rotational thromboelastometry (ROTEM®). In this study, we investigated the effect of fibrinogen concentration and its relative contribution to overall clot strength using ROTEM. METHODS: Blood samples were collected from healthy volunteers. The effects of platelet count on clot strength, determined by… CONTINUE READING
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