The Effects of Difumarate Salt S-15176 after Spinal Cord Injury in Rats

@inproceedings{Erdogan2015TheEO,
  title={The Effects of Difumarate Salt S-15176 after Spinal Cord Injury in Rats},
  author={Hakan Erdogan and Matem Tunçdemir and Bilal Kelten and Osman Cemil Akdemir and Alper Karaoğlan and Erol Taşdemiroğlu},
  booktitle={Journal of Korean Neurosurgical Society},
  year={2015}
}
OBJECTIVE In the present study we analyzed neuroprotective and antiapoptotic effect of the difumarate salt S-15176, as an anti-ischemic, an antioxidant and a stabilizer of mitochondrial membrane in secondary damage following spinal cord injury (SCI) in a rat model. METHODS Three groups were performed with 30 Wistar rats; control (1), trauma (2), and a trauma+S-15176 (10 mg/kg i.p., dimethyl sulfoxide) treatment (3). SCI was performed at the thoracic level using the weight-drop technique… CONTINUE READING
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