The Effects of Aged Garlic Extract on Coronary Artery Calcification Progression

@article{Hom2012TheEO,
  title={The Effects of Aged Garlic Extract on Coronary Artery Calcification Progression},
  author={Christopher Hom and Yanting Luo and Matthew J. Budoff},
  journal={Journal of Nutrition and Food Sciences},
  year={2012},
  volume={2015},
  pages={1-5}
}
Background: Aged Garlic Extract (AGE) has been shown to lower LDL, reduce the progression of coronary atherosclerosis, improve vascular function, and have a favorable effect on oxidative biomarkers. Since AGE has been shown to have several potential anti-atherosclerotic properties, including stimulation of microcirculation in peripheral arteries, it was chosen as the agent of study to evaluate its ability to inhibit progression of coronary atherosclerosis. Objective: No study of sufficient… 
THE EFFECTS OF AGED GARLIC EXTRACT ON CORONARY ARTERY CALCIFICATION PROGRESSION AND BLOOD PRESSURE
TLDR
Evaluated the ability of AGE to inhibit vascular calcification, a marker of plaque formation in human coronary arteries, and concluded that AGE reduces multiple cardiovascular risk factors.
A Review: Garlic Effects on the Cardiovascular System
TLDR
The role garlic has played in the modification of hypertension, hyperlipidemia, inflammatory markers and coronary artery calcium is reviewed, providing a safe treatment option to be considered and an alternative to conventional medication without significant side effects.

References

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TLDR
This small pilot study indicates the potential ability of AGE to inhibit the rate of progression of coronary calcification, as compared to placebo over 1 year, and garlic may prove useful for patients who are at high risk of future cardiovascular events.
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TLDR
AGE+CoQ10 are associated with beneficial effects on inflammatory markers and reduced progression of coronary atherosclerosis and after adjustment for age, gender, conventional cardiac risk factors, and statin therapy, AGE+ coenzyme Q10 was associated with benefit.
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TLDR
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TLDR
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TLDR
AGE+S is associated with a favorable improvement in oxidative biomarkers, vascular function, and reduced progression of atherosclerosis.
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TLDR
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TLDR
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TLDR
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TLDR
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