The Effect of a-Actinin on the Length Distribution of F-Actin

@inproceedings{Biron2004TheEO,
  title={The Effect of a-Actinin on the Length Distribution of F-Actin},
  author={David Biron and Elisha Moses},
  year={2004}
}
Actin filament length distribution in cells is often regulated to fit specific tasks. In comparison to the well-studied regulation of the average filament length (e.g., using capping proteins), controlling the width of the distribution is less well understood. We utilize two complementary methods to measure the effect of a-actinin on the width of the distribution of lengths of F-actin in vitro. Analyzing transmission electron micrographs shows that crosslinking by a-actinin reduces the width of… CONTINUE READING