The Effect of Ursolic Acid on Leishmania (Leishmania) amazonensis Is Related to Programed Cell Death and Presents Therapeutic Potential in Experimental Cutaneous Leishmaniasis.

@article{Yamamoto2015TheEO,
  title={The Effect of Ursolic Acid on Leishmania (Leishmania) amazonensis Is Related to Programed Cell Death and Presents Therapeutic Potential in Experimental Cutaneous Leishmaniasis.},
  author={Eduardo Seiji Yamamoto and Bruno Luiz S. Campos and J{\'e}ssica A. Jesus and Marcia Dalastra Laurenti and Susan Pereira Ribeiro and Esper G Kallas and Mariana Rafael-Fernandes and Gabriela Maria Santos-Gomes and Marcelo Sousa Silva and Deborah P Sessa and Jo{\~a}o Henrique Guilardi Lago and D{\'e}bora Levy and Luiz Felipe Domingues Passero},
  journal={PloS one},
  year={2015},
  volume={10 12},
  pages={e0144946}
}
Among neglected tropical diseases, leishmaniasis is one of the most important ones, affecting more than 12 million people worldwide. The available treatments are not well tolerated, and present diverse side effects, justifying the search for new therapeutic compounds. In the present study, the activity of ursolic acid (UA) and oleanolic acid (OA) were… CONTINUE READING