The Effect of Testosterone on the Formation of Brain Structures

@article{Filov2013TheEO,
  title={The Effect of Testosterone on the Formation of Brain Structures},
  author={B. Filov{\'a} and D. Ostatn{\'i}kov{\'a} and P. Celec and J. Hodosy},
  journal={Cells Tissues Organs},
  year={2013},
  volume={197},
  pages={169 - 177}
}
It has been confirmed in several studies that testosterone can significantly affect brain development. Following metabolism of this hormone by 5α-reductase to dihydrotestosterone, testosterone may act via androgen receptors, or after conversion by aromatase to estradiol, it may act via estrogen receptors. The parts of the brain which are changed under the influence of sex hormones are known as sexually dimorphic nuclei, especially in the preoptic area of the hypothalamus. Nevertheless, evidence… Expand
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