The Effect of Surgical Insertion and Proinflammatory Cytokines on Osteochondral Allograft Survival and Metabolism.

@article{Gitelis2018TheEO,
  title={The Effect of Surgical Insertion and Proinflammatory Cytokines on Osteochondral Allograft Survival and Metabolism.},
  author={Samantha L Gitelis and Ariel M Bodker and Michel P. Laurent and Spencer Saline Kirk and Giuseppe Filardo and Maximilian A. Meyer and Arnavaz A Hakimiyan and Lev Rappoport and Markus A Wimmer and Brian Cole and Susan Chubinskaya},
  journal={Cartilage},
  year={2018},
  volume={9 3},
  pages={
          284-292
        }
}
Objective To investigate the responses of refrigerated osteochondral allograft cartilage (OCA) and fresh cartilage (FC), including cell survival and metabolism, to surgical impaction and proinflammatory cytokines. Design Osteochondral plugs (8 mm diameter) were harvested from prolonged-refrigerated (14-28 days) and fresh (≤24 hours postmortem) human femoral hemicondyles and subjected to a 0.2 N s pneumatic impaction impulse. Cartilage explants were removed from subchondral bone and randomized… CONTINUE READING
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