The Effect of Social Stress on Hippocampal Gene Expression

@article{Chao1993TheEO,
  title={The Effect of Social Stress on Hippocampal Gene Expression},
  author={Helen M. Chao and D. Caroline Blanchard and Robert J. Blanchard and Bruce S. McEwen and Randall R. Sakai},
  journal={Molecular and Cellular Neuroscience},
  year={1993},
  volume={4},
  pages={543-548}
}
The housing of male and female rats in a visible burrow system in which a dominance hierarchy is established and interactions between animals can be monitored provides an effective method by which the behavioral and neuroendocrine effects of social stress can be examined. In this social system, subordinate male rats exhibit plasma corticosterone levels that appear to be chronically elevated relative to the dominant rats in the colonies and compared to singly housed controls. Previous studies… CONTINUE READING

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Chronic social stress alters levels of corticotropin-releasing factor and arginine vasopressin mRNA in rat brain.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 1997
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