The Effect of Social Stress on Hippocampal Gene Expression

  title={The Effect of Social Stress on Hippocampal Gene Expression},
  author={Helen M. Chao and D. Caroline Blanchard and Robert J. Blanchard and Bruce S. McEwen and Randall R. Sakai},
  journal={Molecular and Cellular Neuroscience},
The housing of male and female rats in a visible burrow system in which a dominance hierarchy is established and interactions between animals can be monitored provides an effective method by which the behavioral and neuroendocrine effects of social stress can be examined. In this social system, subordinate male rats exhibit plasma corticosterone levels that appear to be chronically elevated relative to the dominant rats in the colonies and compared to singly housed controls. Previous studies… CONTINUE READING


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The Journal of neuroscience : the official journal of the Society for Neuroscience • 1997
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