The Effect of Salsalate Therapy on Endothelial Function in a Broad Range of Subjects

@inproceedings{Nohria2014TheEO,
  title={The Effect of Salsalate Therapy on Endothelial Function in a Broad Range of Subjects},
  author={Anju Nohria and Scott Kinlay and J. Stewart Buck and Whitney M Redline and Robert Copeland‐Halperin and Sora Kim and Joshua A Beckman},
  booktitle={Journal of the American Heart Association},
  year={2014}
}
BACKGROUND Inflammation is fundamental to the development of atherosclerosis. We examined the effect of anti-inflammatory doses of salicylate on endothelium-dependent vasodilation, a biomarker of cardiovascular risk, in a broad range of subjects. METHODS AND RESULTS We performed a randomized, double-blind, placebo-controlled crossover trial evaluating the effects of 4 weeks of high-dose salsalate (disalicylate) therapy on endothelium-dependent flow-mediated and endothelium-independent… CONTINUE READING

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