The Effect of Perioperative Corticosteroids in Total Hip Arthroplasty: A Prospective Double-Blind Placebo Controlled Pilot Study.

@article{Sculco2016TheEO,
  title={The Effect of Perioperative Corticosteroids in Total Hip Arthroplasty: A Prospective Double-Blind Placebo Controlled Pilot Study.},
  author={Peter Keyes Sculco and Alexander S. McLawhorn and Natasha N Desai and Edwin P. Su and Douglas E. Padgett and Kethy M. Jules-Elys{\'e}e},
  journal={The Journal of arthroplasty},
  year={2016},
  volume={31 6},
  pages={
          1208-1212
        }
}
BACKGROUND Surgery produces a rapid rise in interleukin 6 (IL-6) which may increase the risk of deep vein thrombosis and medical complications. Perioperative corticosteroids suppress IL-6 release in patients undergoing total knee arthroplasty. This study evaluates the effects of a perioperative corticosteroid regimen on IL-6 formation, thrombogenesis, fibrinolysis, and clinical outcomes in patients undergoing unilateral, uncemented, total hip arthroplasty. METHODS Twenty-seven patients (14… CONTINUE READING
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