The Effect of Para-Aminobenzoic Acid on the Chemotherapeutic Activity of the Sulfonamides in Lymphogranuloma Venereum and in Duck Malaria

@article{Seeler1943TheEO,
  title={The Effect of Para-Aminobenzoic Acid on the Chemotherapeutic Activity of the Sulfonamides in Lymphogranuloma Venereum and in Duck Malaria},
  author={A. Seeler and O. Graessle and Edwina D. Dusenbery},
  journal={Journal of Bacteriology},
  year={1943},
  volume={45},
  pages={205 - 209}
}
It is now well established that para-aminobenzoic acid inhibits the action of sulfonamides on bacteria in vitro and in vivo .(Rubbo and Gillespie, 1940; Selbie, 1940; Woods, 1940). Wiedling (1941) found that para-aminobenzoic acid produced an inhibition of the effect of sulfanilamide, sulfapyridine and sulfathiazole on the fresh water diatom Nitzschia palea var. debilis. Experiments published by Dimond (1941) showed that para-aminobenzoic acid interfered with the action of sulfanilamide on the… Expand
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THE mode of action of sulphanilamide has been the subject of much recent work. Possibly the most precise contribution has been Woods's discovery of the anti-sulphanilamide effect of p-amino benzoicExpand
Chemotherapy of Lymphogranuloma Venereum with Sulfonamide Drugs
It was recognized early that in lymphogranuloma venereum, unlike most other virus diseases, some success attended treatment of infected mice or guinea pigs with drugs of the sulfonamide group. TheExpand
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