The Effect of Para-Aminobenzoic Acid on the Chemotherapeutic Activity of the Sulfonamides in Lymphogranuloma Venereum and in Duck Malaria.

@article{Seeler1943TheEO,
  title={The Effect of Para-Aminobenzoic Acid on the Chemotherapeutic Activity of the Sulfonamides in Lymphogranuloma Venereum and in Duck Malaria.},
  author={A. Seeler and O. Graessle and E. Dusenbery},
  journal={Journal of bacteriology},
  year={1943},
  volume={45 3},
  pages={
          205-9
        }
}
It is now well established that para-aminobenzoic acid inhibits the action of sulfonamides on bacteria in vitro and in vivo .(Rubbo and Gillespie, 1940; Selbie, 1940; Woods, 1940). Wiedling (1941) found that para-aminobenzoic acid produced an inhibition of the effect of sulfanilamide, sulfapyridine and sulfathiazole on the fresh water diatom Nitzschia palea var. debilis. Experiments published by Dimond (1941) showed that para-aminobenzoic acid interfered with the action of sulfanilamide on the… Expand
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