The Effect of Oral α-Galactosidase on Intestinal Gas Production and Gas-Related Symptoms

  title={The Effect of Oral $\alpha$-Galactosidase on Intestinal Gas Production and Gas-Related Symptoms},
  author={Michele Di Stefano and Emanuela Miceli and Samantha Gotti and Antonio Missanelli and Samanta Mazzocchi and Gino Roberto Corazza},
  journal={Digestive Diseases and Sciences},
Bloating, abdominal distention, and flatulence represent very frequent complaints in functional disorders but their pathophysiology and treatment are largely unknown. Patients frequently associate these symptoms with excessive intestinal gas and the reduction of gas production may represent an effective strategy. The aim was to evaluate the effect of α-galactosidase administration, in a randomized double-blind placebo-controlled protocol, on intestinal gas production and gas-related symptoms… 

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