The Effect of Newer Serotonin-Noradrenalin Antidepressants on Cytokine Production: A Review of the Current Literature

@article{Berardis2010TheEO,
  title={The Effect of Newer Serotonin-Noradrenalin Antidepressants on Cytokine Production: A Review of the Current Literature},
  author={D. De Berardis and C. Conti and N. Serroni and F. S. Moschetta and L. Olivieri and A. Carano and R. Salerno and M. Cavuto and B. Farina and M. Alessandrini and L. Janiri and G. Pozzi and M. di Giannantonio},
  journal={International Journal of Immunopathology and Pharmacology},
  year={2010},
  volume={23},
  pages={417 - 422}
}
Cytokines may influence brain activities especially during stressful conditions, and elevated levels of IL-6 and C-reactive protein have been pointed out in subjects with Major Depression. If pro-inflammatory cytokines play a causative role in major depressive disorders, one would expect that antidepressants may down-regulate these cytokines or interfere with their actions, leading to improvement of depressive symptoms. Accumulating evidence has been published that antidepressants modulate… Expand
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