The Effect of Microbiota and the Immune System on the Development and Organization of the Enteric Nervous System

@inproceedings{Obata2016TheEO,
  title={The Effect of Microbiota and the Immune System on the Development and Organization of the Enteric Nervous System},
  author={Yuuki Obata and Vassilis Pachnis},
  booktitle={Gastroenterology},
  year={2016}
}
The gastrointestinal (GI) tract is essential for the absorption of nutrients, induction of mucosal and systemic immune responses, and maintenance of a healthy gut microbiota. Key aspects of gastrointestinal physiology are controlled by the enteric nervous system (ENS), which is composed of neurons and glial cells. The ENS is exposed to and interacts with the outer (microbiota, metabolites, and nutrients) and inner (immune cells and stromal cells) microenvironment of the gut. Although the… CONTINUE READING
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