The Effect of Methotrexate in Rheumatoid Arthritis Patients is Reduced by Tea Consumption

@inproceedings{Mikhael2013TheEO,
  title={The Effect of Methotrexate in Rheumatoid Arthritis Patients is Reduced by Tea Consumption},
  author={E. Mikhael and S. I. Mohammed},
  year={2013}
}
Rheumatoid arthritis (RA) is a common inflammatory disease. Methotrexate (MTX) is the most important drug for RA treatment; it acts as anti inflammatory drug by increasing adenosine level. Adenosine receptor antagonists reduce the anti inflammatory effect of MTX. Tea is a popular drink in Iraq contain large amount of caffeine, this study aimed to evaluate the effect of tea consumption on the response to MTX in RA patients. A cross-sectional study was conducted in Baghdad Teaching Hospital… Expand
1 Citations
Modulation of methotrexate efficacy by green tea polyphenols in rat adjuvant arthritis
TLDR
It is suggested that long-term administration of GS may inhibit the therapeutic action of methotrexate in arthritic rats, suggesting a pro-oxidant effect. Expand

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