The Effect of Intensive Treatment of Diabetes on the Development and Progression of Long‐Term Complications in Insulin‐Dependent Diabetes Mellitus

@article{Nathan1993TheEO,
  title={The Effect of Intensive Treatment of Diabetes on the Development and Progression of Long‐Term Complications in Insulin‐Dependent Diabetes Mellitus},
  author={D. Nathan and S. Genuth and J. Lachin and P. Cleary and O. Crofford and M. Davis and L. Rand and C. Siebert},
  journal={Survey of Anesthesiology},
  year={1993},
  volume={38},
  pages={173}
}
BACKGROUND Long-term microvascular and neurologic complications cause major morbidity and mortality in patients with insulin-dependent diabetes mellitus (IDDM. [...] Key MethodMETHODS A total of 1441 patients with IDDM--726 with no retinopathy at base line (the primary-prevention cohort) and 715 with mild retinopathy (the secondary-intervention cohort) were randomly assigned to intensive therapy administered either with an external insulin pump or by three or more daily insulin injections and guided by…Expand
16,035 Citations

Paper Mentions

Interventional Clinical Trial
Type 1 diabetes (T1D), is associated with considerable risk of morbidity and mortality due to chronic hyperglycemia. Despite innovations in management, pediatric patients of African… Expand
ConditionsType1diabetes
InterventionDevice, Other
Interventional Clinical Trial
In this randomized, double-blind, double-dummy, placebo-controlled study, approximately 675 eligible subjects with type 2 diabetes and inadequate control on at least one and up to 3… Expand
ConditionsType 2 Diabetes Mellitus
InterventionDrug, Other
Interventional Clinical Trial
Telemedicine is a solution to overcome distance and ensure the provision of healthcare services. This study aims to investigate the effects of conducting outpatient clinic visits… Expand
ConditionsInsulin Dependent Diabetes Mellitus 1, Telemedicine
InterventionOther
Intensive insulin therapy in insulin-dependent diabetes mellitus, the results of the diabetes control and complications trial.
  • F. Duron
  • Medicine
  • Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
  • 1995
  • 7
Effect of intensive insulin therapy on progression of overt nephropathy in patients with type 1 diabetes mellitus.
  • T. Aoki, E. O. Grecu, +5 authors R. Meisenheimer
  • Medicine
  • Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
  • 1999
  • 8
Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes.
  • 3,478
  • PDF
Long-term effect of diabetes and its treatment on cognitive function.
  • 495
  • PDF
Insulin therapy, hyperglycemia, and hypertension in type 1 diabetes mellitus.
  • 95
  • PDF
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 34 REFERENCES
The Diabetes Control and Complications Trial (DCCT).
  • 417
...
1
2
3
4
...