The Effect of Inducible Nitric Oxide Synthase on Multiterritory Perforator Flap Survival in Rats.

@article{Tao2016TheEO,
  title={The Effect of Inducible Nitric Oxide Synthase on Multiterritory Perforator Flap Survival in Rats.},
  author={Xian-Yao Tao and Long Wang and Wei-yang Gao and Jian Ding and Xiao-Liang Feng and Zong-Wei Zhou and Liang-Hui Yang},
  journal={Journal of reconstructive microsurgery},
  year={2016},
  volume={32 9},
  pages={643-649}
}
Background Inducible nitric oxide synthase (iNOS) plays an important role in vasodilation, angiogenesis, and ischemia-reperfusion injury. We investigated the effects of iNOS on the survival and choke vessels of multiterritory perforator flaps in rats. Methods In this study, 84 rats were divided into two groups of 42 rats each and subjected to multiterritory perforator flap operations. Rats in group A received daily intraperitoneal doses of 100 mg per kg of aminoguanidine (AG) and rats in group… CONTINUE READING