Corpus ID: 40827754

The Effect of Hypothyroid Function on Canine Behavior

  title={The Effect of Hypothyroid Function on Canine Behavior},
  author={L. Aronson and W. Dodds},
Introduction In human medicine, a wide range of behavioral symptoms have been reported in hypothyroid patients. In the early stages of the disease, reduced cognitive function and concentration, together with impaired short-term memory, may be easily confused with attention deficit-hyperactivity disorder (AD/HD) (Hauser et al 1993). Visual and auditory hallucinations can be mistaken for schizophrenia or psychosis. Fear ranging from mild anxiety to frank paranoia; mood swings; and aggression have… Expand
Thyroid dysfunction in attention-deficit hyperactivity disorder and effect of comorbidity
Introduction Attention-deficit hyperactivity disorder (ADHD) is considered to have a biologic basis, but the precise cause is unknown. It is one of the neurodevelopmental abnormalities observedExpand
Children with ADHD have no thyroid profile abnormalities, and there was no significant difference between the study group and their siblings in serum total T3, thyroid-stimulating hormone, T4 (P > 0.05). Expand
The effect of thyroid replacement in dogs with suboptimal thyroid function on owner-directed aggression: A randomized, double-blind, placebo-controlled clinical trial
Abstract The efficacy of thyroid hormone replacement therapy (THRT) as treatment for owner-directed aggression in client-owned dogs with borderline low thyroid hormone levels was evaluated by meansExpand
Exogenous corticosteroids and dog behaviour
The aim of this research was to identify possible behavioural changes in dogs treated with corticosteroids and investigate more rigorously the possible relationship between these signs and Corticosteroid use in dogs. Expand
Comparison of thyroid analytes in dogs aggressive to familiar people and in non-aggressive dogs.
There was no significant difference between aggressive and non-aggressive dogs in the thyroid concentrations most commonly used to diagnose canine hypothyroidism. Expand
Noise Sensitivities in Dogs: An Exploration of Signs in Dogs with and without Musculoskeletal Pain Using Qualitative Content Analysis
Signs of noise sensitivity in dogs with and without musculoskeletal pain are explored by comparing case histories using qualitative content analysis and strong themes emerged relating to widespread generalisation to associated environments and avoidance of other dogs in the “clinical cases,” which did not appear in the "control cases". Expand
Noise sensitivities in dogs: a new licensed treatment option
It is a cause for concern that less than a third of owners have sought help for their dog, and the majority of those who do turn to someone other than their veterinarian, suggesting that a large number of dogs remain untreated for noise sensitivities. Expand


Thyroid hormones, serotonin and mood: of synergy and significance in the adult brain
There is robust evidence, particularly from animal studies, that the thyroid economy has a modulating impact on the brain serotonin system, and one mechanism is postulated through which exogenous thyroid hormones may exert their modulatory effects in affective illness is via an increase in serotonergic neurotransmission. Expand
Attention deficit-hyperactivity disorder in people with generalized resistance to thyroid hormone.
In the study sample, attention deficit-hyperactivity disorder is strongly associated with generalized resistance to thyroid hormone. Expand
Canine behaviors associated with hypothyroidism.
  • B. Beaver, L. Haug
  • Medicine
  • Journal of the American Animal Hospital Association
  • 2003
It is recommended that thyroid gland function be assessed in all dogs presenting with aggression problems, especially those developing slowly in mature animals, and canine hypothyroidism should be a considered differential diagnosis in dogs presenting for suspect canine cognitive dysfunction, as many of the behavioral symptoms are shared. Expand
Effect of acute and chronic treatment with triiodothyronine on serotonin levels and serotonergic receptor subtypes in the rat brain.
After both acute and chronic T3 treatment, serotonin levels increased in the cerebral cortex but not in the hippocampus, which might indicate that thyroid hormones enhance 5-HT concentration in certain brain areas, thus causing a down-regulation of 5- HT2 receptors. Expand
Chronic clomipramine and triiodothyronine increase serotonin levels in rat frontal cortex in vivo: relationship to serotonin autoreceptor activity.
The action of T3 in potentiating the clinical response to TCA drugs may be due to its effect on 5-HT levels in the frontal cortex, which is due to desensitization of the presynaptic 5- HT-1a autoreceptors. Expand
Neuropsychiatric manifestations of altered thyroid state.
The authors assessed the mood and cognitive effects of sequential T4, T3, and withdrawal of thyroid hormone replacement on 25 patients who had had thyroidectomies for thyroid cancer. The patientsExpand
Alterations in thyroid hormone concentrations in healthy sled dogs before and after athletic conditioning.
Although thyroid hormone concentrations remained within the established reference ranges in many of the dogs, values that were outside the reference range in some dogs could potentially lead to an incorrect assessment of thyroid status. Expand
Effects of prednisone on thyroid and gonadal endocrine function in dogs.
Results suggest that LH secretion in dogs is inhibited at the hypothalamic and/or pituitary level by prednisone administration, which consequently results in reduced testosterone concentrations. Expand
Influence of glucocorticoids on TRF-induced TSH response in man.
It is concluded that the mechanism of the glucocorticoid suppressive action on TSH secretion after short-term, low doses of glucoc Corticoid administration may be an impaired secretion of endogenous TRF, which results in a supernormal TSH response induced by exogenous TRF. Expand
The effects of peripheral endocrine hormone deficiencies on the processes of behavior, learning, and memory
  • Y. Fedotova
  • Psychology, Medicine
  • Neuroscience and Behavioral Physiology
  • 2006
Analysis of the results showed that corticosteroid hormones are directly involved in the processes of learning and behavior and sex and thyroid hormones appear to have modulatory effects on higher nervous activity. Expand