The Effect of Genistein on Intracerebroventricular Streptozotocin-Induced Cognitive Deficits in Male Rat


Methods: For this purpose, rats were injected with ICV STZ bilaterally, on days 1 and 3 (3 mg/kg). The STZ-injected rats received GEN (1 mg/kg/day, p.o.) starting one day pre-surgery for two weeks. The learning and memory performance was assessed using passive avoidance paradigm, and for spatial cognition evaluation, radial eight-arm maze (RAM) task was… (More)


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