The Effect of Food on the Bioavailability of Norethindrone and Ethinyl Estradiol from Norethindrone Acetate/Ethinyl Estradiol Tablets Intended for Continuous Hormone Replacement Therapy
@article{Boyd2003TheEO, title={The Effect of Food on the Bioavailability of Norethindrone and Ethinyl Estradiol from Norethindrone Acetate/Ethinyl Estradiol Tablets Intended for Continuous Hormone Replacement Therapy}, author={R. Boyd and E. A. Zegarac and M. Eldon}, journal={The Journal of Clinical Pharmacology}, year={2003}, volume={43} }
As part of the development of a combination product containing norethindrone acetate and low‐dose ethinyl estradiol for continuous hormone replacement therapy in postmenopausal women, a study was conducted to determine the effect of a high‐fat meal on the bioavailability of norethindrone and ethinyl estradiol from tablets containing 1 mg norethindrone acetate/10 μg ethinyl estradiol. Eighteen healthy postmenopausal women participated in an open‐label, single‐dose, randomized, three‐way… CONTINUE READING
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