The Effect of Food on the Bioavailability of Norethindrone and Ethinyl Estradiol from Norethindrone Acetate/Ethinyl Estradiol Tablets Intended for Continuous Hormone Replacement Therapy

@article{Boyd2003TheEO,
  title={The Effect of Food on the Bioavailability of Norethindrone and Ethinyl Estradiol from Norethindrone Acetate/Ethinyl Estradiol Tablets Intended for Continuous Hormone Replacement Therapy},
  author={Rebecca A. Boyd and E A Zegarac and Michael A. Eldon},
  journal={The Journal of Clinical Pharmacology},
  year={2003},
  volume={43}
}
As part of the development of a combination product containing norethindrone acetate and low‐dose ethinyl estradiol for continuous hormone replacement therapy in postmenopausal women, a study was conducted to determine the effect of a high‐fat meal on the bioavailability of norethindrone and ethinyl estradiol from tablets containing 1 mg norethindrone acetate/10 μg ethinyl estradiol. Eighteen healthy postmenopausal women participated in an open‐label, single‐dose, randomized, three‐way… Expand
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