The Effect of Food on Cysteamine Bitartrate Absorption in Healthy Participants.

@article{Dohil2012TheEO,
  title={The Effect of Food on Cysteamine Bitartrate Absorption in Healthy Participants.},
  author={Ranjan Dohil and Betty L. Cabrera and Jon A. Gangoiti and Patrice R. Rioux},
  journal={Clinical pharmacology in drug development},
  year={2012},
  volume={1 4},
  pages={
          170-4
        }
}
OBJECTIVES Treatment with cysteamine reduces the rate of progression to end-stage kidney disease in cystinosis. Although food is often taken with cysteamine to reduce associated gastrointestinal symptoms, this may alter the bioavailability of cysteamine. METHODS This is a prospective, randomized, 3-treatment study to determine the effects of fasting and high-fat/calorie and high-protein meals on cysteamine absorption in healthy adult controls. On 3 separate days, serial plasma cysteamine… CONTINUE READING
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