• Corpus ID: 20204300

The Effect of Coenzyme Q 10 on Morbidity and Mortality in Chronic Heart Failure Results From Q-SYMBIO : A Randomized Double-Blind Trial

@inproceedings{MortensenTheEO,
  title={The Effect of Coenzyme Q 10 on Morbidity and Mortality in Chronic Heart Failure Results From Q-SYMBIO : A Randomized Double-Blind Trial},
  author={Svend Aage Mortensen and Franklin Rosenfeldt and Adarsh Kumar and Peter Dolliner and Krzysztof Jerzy Filipiak and Daniel Pella and Urban Alehagen and G{\"u}nter Steurer and Gian Paolo Littarru}
}
Fro Re leg kF Ko Po Co rel Ma OBJECTIVES This randomized controlled multicenter trial evaluated coenzyme Q10 (CoQ10) as adjunctive treatment in chronic heart failure (HF). BACKGROUND CoQ10 is an essential cofactor for energy production and is also a powerful antioxidant. A low level of myocardial CoQ10 is related to the severity of HF. Previous randomized controlled trials of CoQ10 in HF were underpowered to address major clinical endpoints. METHODS Patients with moderate to severe HF were… 

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