The Effect of Chronic Alcohol Intake on Prognosis and Outcome in Paracetamol Overdose

@article{Bray1991TheEO,
  title={The Effect of Chronic Alcohol Intake on Prognosis and Outcome in Paracetamol Overdose},
  author={G. Bray and C. Mowat and D. Muir and J. Tredger and R. Williams},
  journal={Human \& Experimental Toxicology},
  year={1991},
  volume={10},
  pages={435 - 438}
}
1 In a retrospective study, we stratified 79 patients with paracetamol hepatotoxicity into two groups according to weekly alcohol consumption below (n = 49) or above (n = 30) Royal College of Physicians' guidelines of 21 units week -1 for males and 14 for females. 2 Survival was lower (33%) and serum creatinine on admission higher (median 207 μmol) in patients whose alcohol consumption was above recommended guidelines than in those whose drank less than this (65.9% and 138 μmol, P < 0.01 and P… Expand
Acute ethanol coingestion confers a lower risk of hepatotoxicity after deliberate acetaminophen overdose.
Comment on "Acute ethanol coingestion confers a lower risk of hepatotoxicity after deliberate acetaminophen overdose".
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