The Effect of Anabolic Steroids and Corticosteroids on Healing of Muscle Contusion Injury

  title={The Effect of Anabolic Steroids and Corticosteroids on Healing of Muscle Contusion Injury},
  author={John M. Beiner and Peter Jokl and Jacek Cholewicki and Manohar M. Panjabi},
  journal={The American Journal of Sports Medicine},
  pages={2 - 9}
The effect of an anabolic steroid (nandrolone decanoate, 20 mg/kg) and a corticosteroid (methylprednisolone acetate, 25 mg/kg) on healing muscle injured with a drop-mass technique in a reproducible muscle contusion injury model in the rat was studied. Healing was determined by measuring active contractile tension in each muscle and histologic analysis. At day 2, the corticosteroid group showed significant improvement in both twitch and tetanic strength relative to the controls. At day 7, this… 

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