The Edinburgh human metabolic network reconstruction and its functional analysis

@article{Ma2007TheEH,
  title={The Edinburgh human metabolic network reconstruction and its functional analysis},
  author={Hongwu Ma and Anatoly Sorokin and Alexander Mazein and Alex Selkov and Evgeni Selkov and Oleg V. Demin and Igor Goryanin},
  journal={Molecular Systems Biology},
  year={2007},
  volume={3},
  pages={135 - 135}
}
A better understanding of human metabolism and its relationship with diseases is an important task in human systems biology studies. In this paper, we present a high-quality human metabolic network manually reconstructed by integrating genome annotation information from different databases and metabolic reaction information from literature. The network contains nearly 3000 metabolic reactions, which were reorganized into about 70 human-specific metabolic pathways according to their functional… CONTINUE READING
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