The Eck receptor tyrosine kinase is implicated in pattern formation during gastrulation, hindbrain segmentation and limb development.

@article{Ganju1994TheER,
  title={The Eck receptor tyrosine kinase is implicated in pattern formation during gastrulation, hindbrain segmentation and limb development.},
  author={Pam Ganju and Kazuhiro Shigemoto and Jack Brennan and A. R. Entwistle and Alastair D. Reith},
  journal={Oncogene},
  year={1994},
  volume={9 6},
  pages={1613-24}
}
Members of the protein superfamily of transmembrane receptor tyrosine kinases are key components of intercellular signal transduction pathways that elicit appropriate cellular responses to environmental cues during development of multicellular organisms. In a search for additional receptor tyrosine kinases expressed during mouse embryogenesis we cloned the murine homolog of Eck, a member of the Eph subfamily, that maps to the distal region of mouse chromosome 4. Specific antisera defined Eck in… CONTINUE READING

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