The Early History of Cardiac Surgery in Stockholm

  title={The Early History of Cardiac Surgery in Stockholm},
  author={Kjell R{\aa}degran},
  journal={Journal of Cardiac Surgery},
  • K. Rådegran
  • Published 1 November 2003
  • Medicine
  • Journal of Cardiac Surgery
Abstract  Cardiac surgery in Stockholm grew on a sound foundation of well‐developed general thoracic surgery. The portal figure is Clarence Crafoord (1899–1983) who already in 1927 had succeeded with the Trendelenburg pulmonary embolectomy operation. He went on to develop lung surgery in general. With foresight he stimulated the chemists of Karolinska Institute to purify heparin, first for prophylaxis against venous thromboembolism and later for use with the heart‐lung machine. In 1944 he… 

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Approximately one hundred and forty-two Trendelenburg operations for massive pulmonary embolism have been reported, and only nine of the patients operated on have left the hospital as cured. 1 This


The use of heparin as prophylactic against thrombosis has arisen through our increased knowledge of this substance gained during the last few years. The latest developments in this field have been

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