The ERK-1/2 signaling pathway is involved in the stimulation of branching morphogenesis of fetal mouse submandibular glands by EGF.

@article{Kashimata2000TheES,
  title={The ERK-1/2 signaling pathway is involved in the stimulation of branching morphogenesis of fetal mouse submandibular glands by EGF.},
  author={Masanori Kashimata and Shariq Sayeed and Albuquerque Ka and A Onetti-Muda and Hiroshi Sakagami and Tullio Faraggiana and Edward W. Gresik},
  journal={Developmental biology},
  year={2000},
  volume={220 2},
  pages={
          183-96
        }
}
We have previously reported that epidermal growth factor (EGF) stimulates branching morphogenesis of the fetal mouse submandibular gland (SMG) (M. Kashimata and E. W. Gresik, 1997, Dev. Dyn. 208, 149-161) and that the EGF receptor (EGFR) is localized principally, if not exclusively, on the epithelial components of the fetal SMG (E. W. Gresik, M. Kashimata, Y. Kadoya, R. Mathews, N. Minami, and S. Yamashina, 1997, J. Histochem. Cytochem. 45, 1651-1657). The EGFR is a receptor tyrosine kinase… CONTINUE READING