The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.

@article{Aronson2008TheET,
  title={The ECLIPSE trials: comparative studies of clevidipine to nitroglycerin, sodium nitroprusside, and nicardipine for acute hypertension treatment in cardiac surgery patients.},
  author={Solomon Aronson and Cornelius McKown Dyke and Kevin A Stierer and Jerrold H Levy and Albert T. Cheung and Philip D. Lumb and Dean J Kereiakes and Mark F. Newman},
  journal={Anesthesia and analgesia},
  year={2008},
  volume={107 4},
  pages={1110-21}
}
BACKGROUND Acute hypertension during cardiac surgery can be difficult to manage and may adversely affect patient outcomes. Clevidipine is a novel, rapidly acting dihydropyridine L-type calcium channel blocker with an ultrashort half-life that decreases arterial blood pressure (BP). The Evaluation of CLevidipine In the Perioperative Treatment of Hypertension Assessing Safety Events trial (ECLIPSE) was performed to compare the safety and efficacy of clevidipine (CLV) with nitroglycerin (NTG… CONTINUE READING