The E7-associated cell-surface antigen: a marker for the 11p13 chromosomal deletion associated with aniridia-Wilms tumor.

@article{Scoggin1985TheEC,
  title={The E7-associated cell-surface antigen: a marker for the 11p13 chromosomal deletion associated with aniridia-Wilms tumor.},
  author={Charles H. Scoggin and James H. Fisher and S A Shoemaker and H E Morse and T Brian Leigh and Vincent Michael Riccardi},
  journal={American journal of human genetics},
  year={1985},
  volume={37 5},
  pages={883-9}
}
Unbalanced interstitial deletions of the p13 region of human chromosome 11 have been associated with congenital hypoplasia or aplasia of the iris, mental retardation, ambiguous genitalia, and predisposition to Wilms tumor of the kidney. Utilizing somatic cell hybrids containing either the normal or abnormal chromosome 11 from a child with Wilms tumor and aniridia, we previously mapped the E7 cell-surface antigen to the 11p1300-to-11p15.1 region. To localize even further the site of this antigen… CONTINUE READING